By applying Granger-causality and network analysis to live calcium imaging of endothelial cell monolayers we found that increased connectivity, heterogeneity, and memory, at the cellular scale, were associated with the emergence of synchronization across a multicellular network by gradual transition from local to global information spread!
The manuscript was led by Amos Zamir and is a joint project with Bo Sun from Oregon State University.
Twitter summary: https://twitter.com/AssafZaritsky/status/1554695480747196417
